Amino functionalized mesoporous silica for drug adsorption

N. Benyoub, A. Benhamou, A. Debab

Abstract


The main objective of this work was to synthesize hexagonal mesoporous materials such as MCM-41 from optimized protocols and to test their effectiveness in adsorption of different pharmaceutical pollutants. First, pore size and the specific surface area of the base materials have been modified by incorporation of amino groups in post-synthesis, by selective extraction of the loaded groups and finally by calcination. Subsequently, adsorbent products were characterized by their mesoscopic textures, structures and controls using different methods: X-Ray Diffraction (XRD), Specific Surface Area (BET), Fourier Transform Infrared Spectroscopy (FTIR), Thermogravimetric analyses (TGA/DTA) and Zetametry. Finally, their adsorption capacities were evaluated using several pharmaceutical residues under standard conditions (such as Diclofenac, Cefalexin ...). The results obtained during the adsorption study showed the effectiveness of these materials for the decontamination of aqueous media contaminated with pharmaceutical residues. Kinetic and adsorption isotherm studies were carried out to clarify the method of binding of the selected pharmaceutical pollutants to the tested materials.

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